Jayakumar Rajadas
Academic Appointments
- Director, BioADD and Assistant Director of CV Pharmacology, Dean's Office - Educational Programs and Services (EPS), Biomaterials and Advanced Drug Delivery (BioADD) Service Center
Key Documents
Contact Information
- Contact Information
Personal Information Email Tel (650) 724-6806
Professional Overview
Professional Interests
Dr. Rajadas is currently working on the molecular mechanism of neurodegenerative disorders caused by aggregated tau and abeta proteinsproteins that are synergically involved in Alzheimers disease development. He uses various biophysical approaches such as AFM, fluorescence, and NMR to understand the structural details of neurotoxic oligomeric forms of these two proteins.
For the last 7 years, our lab has also been involved in transforming biophysical ideas into biomaterial and drug delivery technologies. These technologies include microencapsulation of drugs, vascular grafts, bio-implants, development of small molecule and protein-based drugs, regeneration of nerve and cardiovascular tissues, and wound healing applications
Education and Certifications
| M,S: | University of Madras, Chemistry (1983) |
| Ph.D: | Indian Institute of Technology, Biophysical Chemistry (1990) |
Internet Links
Honors and Awards
- TANSA Award, Government of Tamil Nadu, India (1999)
- Young Scientist Award in Chemistry, Council of Scientific and Industrial Research, India (1996)
- SPARK award, Stanford (2009, 2011, 2012)
Work Experience
- Director, Biomaterials and Advanced Drug Delivery Lab, Stanford School of Medicine (2010 - present)
- Assistant Director, Cardiovascular Pharmacology, Stanford school of medicine (2013 - present)
- Lecturer, Neurology and Neurological Sciences, Stanford school of medicine (2012 - present)
- Instructor, Neurology and Neurological Sciences, Stanford University School of Medicine (2007 - 2012)
- Consulting Professor, Department of Chemical Engineering, Stanford University (2005 - 2007)
- Visiting Professor, Department of Biological Sciences, Stanford University (2003 - 2005)
Publications
- Channelrhodopsins: visual regeneration and neural activation by a light switch. N Biotechnol. 2013
- Enhanced Aβ(1-40) production in endothelial cells stimulated with fibrillar Aβ(1-42). PLoS One. 2013; (3): e58194
- Polyvinylpyrrolidone microneedles enable delivery of intact proteins for diagnostic and therapeutic applications. Acta Biomater. 2013
- A critical role for the PAR-1/MARK-tau axis in mediating the toxic effects of Aβ on synapses and dendritic spines. Hum Mol Genet. 2012; (6): 1384-90
- Chaperone activity of small heat shock proteins underlies therapeutic efficacy in experimental autoimmune encephalomyelitis. J Biol Chem. 2012; (43): 36423-34
- Enhancement of mesenchymal stem cell angiogenic capacity and stemness by a biomimetic hydrogel scaffold. Biomaterials. 2012; (1): 80-90
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