Department: Obstetrics & Gynecology

primary ovarian insufficiency, premature ovarian failure, health policy, infertilty, assisted reproductive technology, ovulation induction, hormone therapy

Development of improved embryo culture conditions in vitro. Blastocyst cultures. Embryo metabolism in vitro. Embryo maternal dialogue. Clinical application and integration of extended embryo culture systems. Monozygotic twinning. Prevention of multiple pregnancy. Sperm motility enhancers. Fluorescent and non-fluorescent markers of sperm morphology and viablility. Oocyte cryopreservation. Fertility preservation. Improving IVF outcome.

Neonatology, patent ductus arteriosus, pulmonary hypertension of the newborn, infant ventilation, neonatal clinical protocols/clinical pathways.

prenatal diagnosis, genetics, clinical obstetrics

Improving Access to Family Planning Services in Low Resource Settings: Through a collaboration with Population Services International, the Stanford Program for International Reproductive Education and Services (SPIRES) provides technical direction in a program designed to improve access to and uptake of family planning, particularly Long Acting Reversible Contraception (LARC) such as IUDs and implants, in 14 developing countries globally. The first year saw insertion of over 280,000 IUDs.

Special interest in women with vulvodynia and other genital pain disorders.

Regionalization of healthcare to improve obstetric outcomes Magnesium sulfate pharmacokinetics and pharmacodynamics Cancer in pregnancy

Dr. Chen’s research examines the molecular causes of urinary incontinence and pelvic floor dysfunction. Recognizing that urinary incontinence linked to demise of smooth muscle sphincter function, she is investigating the potential use of stem cell regeneration to restore muscle capacity.

Rh disease, other red call isoimmunization, e.g. Kell, etc. I.T.P. and alloimmune thrombocytopenia Multiple pregnancy (twins, triplets, etc.) and associated problems and procedures Ultrasound referrals -- complicated and routine Procedures --cordocentesis, intrauterine transfusion; selective termination or reduction in multiple pregnancy.

Using various animal models of bladder outlet obstruction as a representation of human prostatic disease, I am investigating how intervening with pharmacotherapy, neuromodulation, and other novel therapies may help to reverse the adverse changes in the bladder due to the obstruction. I also am investigating new, minimally invasive treatments for post-prostatectomy urinary incontinence. I am also investigating the role of neruomodulation in the treatment of chronic pelvic pain and IC.

Associate to Visiting Scholars , Postdoctoral Scholars and Medical Fellows

Special interest in Ob simulation as a teaching and training tool.

Director of Finance & Administration, Department of Obstatrics & Gynecology

Antepartum and intrapartum fetal monitoring Prenatal diagnosis Medical complications of pregnancy, particularly: SLE, hypertension, diabetes, malignancy A.

High Risk Obstetrics: preterm labor, preeclampsia, medical and surgical complications of pregnancy, prenatal diagnosis and therapy

Gynecologic and obstetric infections.

During the last five years, we have identified several small molecules that kill VHL deficient renal cancer cells through a synthetic lethal screening approach. Another major interest of my laboratory is in identifying hypoxia-induced genes involved in invasion and metastases. We are also investigating how hypoxia regulates gene expression epigenetically.

1. use of mannequin- and virtual reality-based simulation to improve human performance in dynamic domains such as the delivery room 2. use of mannequin- and virtual reality-based simulation to enhance patient safety 3. evaluation and optimization of debriefing 4. evaluation and optimization of scenario design 5. patient simulator design 6. device simulator design

Distributed learning of anatomy and laparoscopic surgery; surgical simulation; team-training in virtual environments;telemedicine for acute & chronic disease management in virtual environments

1) Early childhood neurodevelopmental outcomes, mortality and morbidities of ELBW, extremely premature, and high-risk infants; predictive clinical factors, evidence-based interventions 2) Use of advanced neuroimaging techniques in the premature and term infant; diagnostic findings, and predictors of neurodevelopmental outcomes 3) Advanced therapeutic modalities: HFOV, iNO, ECMO - implementation, indications, outcomes 4) Natural history and outcomes of complex fetal anomalies

Hormonal regulation of ovarian function; gonadotropin receptors and related genes, bioinformatic ananlyses of polypeptide hormones and receptors, follicle recruitment and GDF-9; analysis of oocyte and ovarian-expressed genes.

I am interested in prenatal genetic screening and diagnosis.