Community Academic Profiles

Department: Genetics

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  • Academic Appointments Postdoctoral Research fellowGenetics
    Research Interest

    My research area is the genetic epidemology of musculoskeletal and endocrine disease, with a special focus on osteoporosis and diabetes-related bone disease. I have been a representative researcher for the Rotterdam Study (the Netherlands) in several collaborative consortia, including: GEFOS: Genetic Factors for Osteoporosis; GENOMOS: Genetic Markers for Osteoporosis; CHARGE: Cohorts for Heart and Aging Research in Genomic Epidemiology; NCHA: Netherlands Consortium for Healthy Ageing.

  • Academic Appointments Associate Professor (Teaching),  Genetics
    Member,  Bio-X
    Research Interest

    While my primary role is to direct the MS in Human Genetics and Genetic Counseling program, my research focuses on the intersection between genetics and ethics, particularly around the translation of new genetic technologies (such as genome sequencing or non-invasive prenatal diagnosis) into clinical practice. I am especially interested in patient decision making, informed consent, and the interface between genetics and disability.

  • Academic Appointments MD Student, expected graduation Spring 2014
    Ph.D. Student in Genetics, admitted Autumn 2010
  • Academic Appointments Postdoctoral Research fellowGenetics
    Research Interest

    Acetaminophen – Tylenol™ - is an OTC drug used for its analgesic and antipyretic effects. APAP overdose has been reported to cause liver injury, acute liver failure and over 450 deaths yearly in the United State. Implicated its toxicity is N-acetyl-p-benzoquinone imine (NAPQI) one of its metabolites excreted by GSH. We propose that administration of formulated NAC-APAP drug may mitigate toxic effect seen in inadvertent APAP overdose via NAC mediated replenishment of intracellular GSH.

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