Community Academic Profiles

Department: Genetics

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  • Academic Appointments Ph.D. Student in Genetics, admitted Autumn 2005
  • Academic Appointments Postdoctoral Research fellowGenetics
    Research Interest

    Stem cell function requires both the establishment and maintenance of particular epigenetic states. Perturbation of the epigenetic status of stem cells may compromise both self-renewal and multipotency. Work from our lab has identified the Forkhead family transcription factor, FoxO3, as a regulator of adult neural stem cell (NSCs) quiescence, which prevents the depletion of this population of cells. Along with recent evidence that Forkhead family members act as ‘pioneer factors’ in the opening ..

  • Academic Appointments Postdoctoral Research fellowGenetics
  • Academic Appointments Assistant Professor,  Genetics
    Member,  Bio-X
    Research Interest

    Our laboratory uses genome-wide methods to uncover alterations that drive cancer progression and metastasis in genetically-engineered mouse models of human cancers. We combine cell-culture based mechanistic studies with our ability to alter pathways of interest during tumor progression in vivo to better understand each step of metastatic spread and to uncover the therapeutic vulnerabilities of advanced cancer cells.

  • Academic Appointments Postdoctoral Research fellowGenetics

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