School of Medicine

Showing 1-10 of 24 Results

  • Maya Adam

    Maya Adam

    Lecturer, Pediatrics - Infectious Diseases

    Bio Maya Adam MD has been teaching at Stanford University since 2009. She received her BA in Human Biology from Stanford before studying medicine at the University of British Columbia in Vancouver, Canada. Prior to her post-secondary studies, she spent 10 years as a professional ballet dancer with the State Theater of Saxony in Germany.
    At the Stanford School of Medicine, Adam creates online educational content for the Re-imagining Medical Education Project, led by Charles Prober MD, Senior Associate Dean for Medical Education. In the Program in Human Biology, Adam teaches courses on child health and nutrition. In 2013, Adam created the free, massive open online course Stanford Child Nutrition and Cooking, a public health education outreach effort that has reached more than 230,000 international students. She is also the founder of a non-profit organization called Just Cook for Kids. In 2014, Adam started applying the new teaching technologies being developed at Stanford to the creation of digital teaching tools designed to support the work of international community health workers. The resulting Stanford Health Outreach App is now being used by community health organizations in South Africa and Guatemala and the teaching videos associated with the app have been translated into Xhosa, Spanish and Hindi. In 2015 Adam created the online CME course Food and Medicine and the parallel open online course, Food and Health. She is the author of Food Love Family: A Practical Guide to Child Nutrition.

  • Manuel Amieva

    Manuel Amieva

    Associate Professor of Pediatrics (Infectious Diseases) and of Microbiology and Immunology

    Current Research and Scholarly Interests My laboratory studies the strategies pathogens utilize to colonize and subvert the epithelial barrier. We have focused on the epithelial junctions as a target for bacterial pathogens, since the cell-cell junctions serve as both a barrier to infection and also a major control site for epithelial function. In particular, we are interested in how the gastric pathogen Helicobater pylori may cause cancer by interfering with cell signaling at the epithelial junctions. We are also studying how various bacteria cross and invade the epithelium. For example, we recently found that Listeria monocytogenes targets a specialized subset of cell-cell junctions at the tip of the intestinal villi to find its receptor for invasion. We are interested in determining whether this mode of gastrointestinal invasion of the epithelium is also used by other gastrointestinal pathogens.

  • Ann M. Arvin

    Ann M. Arvin

    Vice Provost and Dean of Research, Lucile Salter Packard Professor of Pediatrics and Professor of Microbiology and Immunology

    Current Research and Scholarly Interests Our laboratory investigates the pathogenesis of varicella zoster virus (VZV) infection, focusing on the functional roles of particular viral gene products in pathogenesis and virus-cell interactions in differentiated human cells in humans and in Scid-hu mouse models of VZV cell tropisms in vivo, and the immunobiology of VZV infections.

  • Sharon F. Chen

    Sharon F. Chen

    Clinical Associate Professor, Pediatrics - Infectious Diseases

    Current Research and Scholarly Interests My research interest is in viral infections commonly affecting immunocompromised patients, investigating viral pathogenesis and anti-viral immunity. As Co-director of the Pediatric Infectious Diseases Program in Immunocompromised Hosts, I develop and conduct clinical studies to establish best practices. I am also the Co-Chair for a multi-institution microbiology and immunology curriculum development project (with the Robert Wood Johnson Foundation) that aims to re-imagine how medical students.

  • Despina Contopoulos-Ioannidis, MD

    Despina Contopoulos-Ioannidis, MD

    Clinical Associate Professor, Pediatrics - Infectious Diseases

    Current Research and Scholarly Interests Evidence based medicine Systematic reviews Meta-analyses
    Outcome research
    Comparative effectiveness
    Comparative safety research
    Chronic Antibiotic Use and Weight Gain
    Family outbreaks and Epidemiology of acute toxoplasmosis in US
    Congenital toxoplasmosis: Improving laboratory dx
    Trends in intussusception in the US (association with pediatric vaccines)
    Empirical appraisal of CEA for pediatric vaccines (with and without inlcusion of herd immunity

  • Cornelia L. Dekker, M.D.

    Cornelia L. Dekker, M.D.

    Professor (Research) of Pediatrics (Infectious Diseases)

    Current Research and Scholarly Interests The Stanford-LPCH Vaccine Program provides an infrastructure for conducting clinical studies of vaccines in children and adults. We conduct immunology studies of seasonal influenza vaccines in twins, in a longitudinal cohort of young and elderly adults and studies of various vaccine candidates for NIH and industry. Additionally, we were a CDC Clinical Immunization Safety Assessment site for 10 years working on safety issues concerning licensed vaccines.

  • Elizabeth Egan

    Elizabeth Egan

    Assistant Professor of Pediatrics (Infectious Diseases)

    Current Research and Scholarly Interests Severe malaria caused by Plasmodium falciparum is a leading cause of morbidity and mortality in the developing world, particularly among young children and pregnant women. Population genetic studies dating back to the mid-20th century first proposed that erythrocytes (red blood cells), the host cell for P. falciparum, have been under natural selection due to malaria. Hemoglobinopathies, thalassemias, ovalocytosis, and G6PD deficiency are all examples of red cell pathologies that are believed to provide protection against severe malaria.

    Although the notion that malaria has helped shape the human genome is well- accepted, the lack of a nucleus in human erythrocytes has hindered our ability to study genetic interactions between these unusual host cells and P. falciparum parasites. Recently, we developed a hematopoietic stem cell-based approach to tackle this issue, in which we can genetically alter nucleated hematopoietic precursor cells and differentiate them ex-vivo to mature erythrocytes that can be infected by P. falciparum. Using this approach, we performed a forward genetic screen of human blood groups to identify critical host factors for P. falciparum, and discovered several candidates that appear to be required for efficient parasite invasion of red blood cells. We found that the Cromer blood group antigen CD55 (DAF) is essential for parasite invasion and is necessary for proper attachment of merozoites to the erythrocyte surface. Importantly the requirement for CD55 appears to be strain-transcendent, suggesting that it may act as a critical receptor during malaria infection.

    We are currently pursuing fundamental questions related to host-pathogen interactions in malaria, with the host erythrocyte as a focal point. We employ a variety of approaches spanning molecular parasitology, stem cell biology, cell biology, biochemistry and genomics. We welcome self-motivated individuals interested in joining us as we seek to learn more about the fascinating biology underlying host-pathogen interactions in malaria.

  • Hayley Gans

    Hayley Gans

    Clinical Associate Professor, Pediatrics - Infectious Diseases

    Current Research and Scholarly Interests The focus of my laboratory is the immune response to viral vaccines evaluating the ontogeny of responses in infants and limitations in immunocompromised hosts. We have studied responses to an early two-dose measles immunization, one versus 2 doses of varicella immunization, and polio vaccine in preterm versus term infants. Other active areas of research include measles and varicella immunity in HIV infected individuals, and transplant recipients.