School of Medicine
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Mark A. Kay, M.D., Ph.D.
Dennis Farrey Family Professor in Pediatrics, and Professor of Genetics
Current Research and Scholarly Interests Mark A. Kay, M.D., Ph.D. Director of the Program in Human Gene Therapy and Professor in the Departments of Pediatrics and Genetics. Respected worldwide for his work in gene therapy for hemophilia, Dr. Kay and his laboratory focus on establishing the scientific principles and developing the technologies needed for achieving persistent and therapeutic levels of gene expression in vivo. The major disease models are hemophilia, hepatitis C, and hepatitis B viral infections.
Assistant Professor of Pediatrics (Human Gene Therapy), of Bioengineering and, by courtesy, of Chemical and Systems Biology
Current Research and Scholarly Interests Our lab applies biochemical and engineering principles to the development of protein-based tools for molecular imaging and gene therapy. Topics of investigation include fluorescent proteins structure and biophysics, fluorescent protein-based biosensors, spatiotemporal analysis of protein translation pathways, chemical control of protein translation, and light-responsive proteins.
Professor of Pediatrics (Human Gene Therapy) at the Lucile Salter Packard Children's Hospital
Current Research and Scholarly Interests Molecular mechanisms and intracellular pathways of antigen processing and presentation; structure/function of HLA-DR,-DM, -DO; mechanisms underlying HLA allele association with disease; disease mechanisms in systemic idiopathic juveile arthritis, recently found to be an HLA-linked disease.