School of Medicine
Showing 1-10 of 16 Results
Associate Professor (Research) of Radiology (General Radiology)
Current Research and Scholarly Interests To develop novel molecular imaging probes and techniques for non-invasively early detection of cancer using multimodality imaging technologies including PET, SPECT, MRI, optical imaging, etc.
Frederick T. Chin, Ph.D.
Assistant Professor (Research) of Radiology (General Radiology)
Current Research and Scholarly Interests Our group's primary objectives are:
1) Novel radioligand and radiotracer development.
We will develop novel PET (Positron Emission Tomography) imaging agents with MIPS and Stanford faculty as well as other outside collaborations including academia and pharmaceutical industry. Although my personal research interests will be to discover and design of candidate probes that target molecular targets in the brain, our group focus will primarily be on cancer biology and gene therapy. In conjunction with our state-of-the-art imaging facility, promising candidates will be evaluated by PET-CT/MR imaging in small animals and primates. Successful radioligands and/or radiotracers will be extended towards future human clinical applications.
2) Designing new radiolabeling techniques and methodologies.
We will aim to design new radiolabeling techniques and methodologies that may have utility for future radiopharmaceutical development in our lab and the general radiochemistry community.
3) Radiochemistry production of routine clinical tracers.
Since we also have many interests with many Stanford faculty and outside collaborators, our efforts will also include the routine radiochemistry production of many existing radiotracers for human and non-human use. Our routine clinical tracers will be synthesized in custom-made or commercial synthetic modules (i.e. GE TRACERlab modules) housed in lead-shielded cells and be distributed manually or automatically (i.e. Comecer Dorothea) to our imagers.
Sanjiv Sam Gambhir, MD, PhD
Virginia and D.K. Ludwig Professor for Clinical Investigation in Cancer Research and Professor, by courtesy, of Bioengineering and of Materials Science and Engineering
Current Research and Scholarly Interests My laboratory focuses on merging advances in molecular biology with those in biomedical imaging to advance the field of molecular imaging. Imaging for the purpose of better understanding cancer biology and applications in gene and cell therapy, as well as immunotherapy are all being studied. A key long-term focus is the earlier detection of cancer by combining in vitro diagnostics and molecular imaging.
Michael L. Goris
Professor of Radiology (Nuclear Medicine), Emeritus
Current Research and Scholarly Interests Radio-immunotherapy. Medical Imaging Processing. Quantification for diagnosis Clinical validations
Michelle L. James, PhD
Instructor, Radiology- Molecular Imaging Program at Stanford
Current Research and Scholarly Interests My research is focused on developing and evaluating molecular imaging agents to improve the way we diagnose, treat, and understand brain diseases.
Sri-Rajasekhar (Raj) Kothapalli, PhD
Instructor, Radiology- Molecular Imaging Program at Stanford
Current Research and Scholarly Interests My research is focused on developing nonionizing and low cost medical technologies that reliably detect the disease and also capable of predicting the prognosis. Towards this goal, I work at the interface of Photonics, Acoustics, MEMS, Molecular Imaging, Medical Imaging and Computing. Equal emphasis is on translating these technologies for pre-clinical and clinical applications in cancer and neurological diseases.
At Stanford, I invented a transrectal ultrasound and photoacoustic (TRUSPA) device for imaging human prostate using capacitive micromachined ultrasonic transducer (CMUT) array technology. Pilot clinical studies on prostate cancer patients demonstrated that the device is capable of simultaneously displaying anatomical and molecular information of the prostate. Currently relevant molecular imaging approaches are being investigated to further improve the sensitivity and specificity of the prostate cancer detection. Similarly I also developed an intraoperative ultrasound and photoacoustic (iUSPA) device that is in the path to clinical translation for various applications.
My other research interests include Cerenkov luminescence imaging and developing novel in vitro diagnostic technologies for detecting the disease in biological fluids and single cancer cells.
Shivaani Kummar, MD, FACP
Professor of Medicine (Oncology) and of Radiology (Molecular Imaging Program at Stanford) at the Stanford University Medical Center
Current Research and Scholarly Interests Dr. Kummar’s research interests focus on developing novel therapies for cancer. She specializes in conducting pharmacokinetic and pharmacodynamic driven first-in-human trials tailored to make early, informed decisions regarding the suitability of novel molecular agents for further clinical investigation. Her studies integrate genomics and laboratory correlates into early phase trials. She is interested in alternate trial designs to facilitate rational drug selection based on human data and help expedite drug development timelines. She has published numerous articles in medical journals and serves on a number of national and international scientific committees.
Professor of Radiology (Molecular Imaging Program at Stanford/Nuclear Medicine) and, by courtesy, of Physics, of Electrical Engineering and of Bioengineering
Current Research and Scholarly Interests Molecular Imaging Instrumentation
Our research interests involve the development of novel instrumentation and software algorithms for in vivo imaging of cellular and molecular signatures of disease in humans and small laboratory animal subjects.
Professor of Biomedical Data Science and, by courtesy, of Radiology (Molecular Imaging)
Current Research and Scholarly Interests Biostatistics, clinical trials, statistical evaluation of medical diagnostic tests, radiology, osteoporosis, meta-analysis, medical decisoin making
Sanjay V. Malhotra, PhD
Associate Professor (Research) of Radiation Oncology (Radiation and Cancer Biology) and of Radiology (Molecular Imaging Program at Stanford)
Current Research and Scholarly Interests My research interests focus on the design and discovery of synthetic, and natural product inspired small molecules which can be used as probes for developing understanding of biological phenomena, including protein-protein interactions and modulation of signal transduction pathways. My laboratory employs the tools of synthetic medicinal chemistry, molecular modeling and chemical biology for translational research in drug discovery, development, imaging and radiation.