School of Medicine
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Rachel J. Hagey
Ph.D. Student in Microbiology and Immunology, admitted Autumn 2011
Current Research and Scholarly Interests My primary research focus is in translational molecular virology, with a special interest in uncovering and characterizing RNA structure-function relationships and their role in RNA virus life cycles. Just as many current antibiotics target RNA secondary structures, I envisage a completely new class of antivirals that will similarly target critical RNA secondary structures within viral genomes (such as packaging, translation, or replication signals). To pursue these goals, my research combines molecular virology and genetic tools with emerging high-throughput RNA structure-probing technologies to uncover new classes of conserved viral, non-protein targets for the development of much needed antiviral therapies.