School of Medicine
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Jorge A. Caballero
Clinical Instructor, Anesthesiology, Perioperative and Pain Medicine
Bio Currently Medical Director at Amino, a consumer healthcare company that aims to revolutionize the way people find doctors for themselves and their loved ones.
Lawrence Chu, MD, MS
Associate Professor of Anesthesiology, Perioperative and Pain Medicine at the Stanford University Medical Center
Current Research and Scholarly Interests I have two lines of research, one involving educational informatics and use of technology in postgraduate medical education and another involving NIH-funded work in patient-oriented clinical research regarding opioid use and physiologic responses associated with acute and chronic exposure in humans.
For a full description of my educational informatics work, please see my website aim.stanford.edu.
My clinical research focuses on the study opiate-induced hyperalgesia in patients suffering from chronic pain.
I am currently conducting an NIH-funded five year double-blinded randomized controlled clinical study (NIGMS award 1K23GM071400-01) that prospectively examines the following hypotheses: 1) pain patients on chronic opioid therapy develop dose-dependent tolerance and/or hyperalgesia to these medications over time, 2) opiate-induced tolerance and hyperalgesia develop differently with respect to various types of pain, 3) opioid-induced hyperalgesia occurs independently of withdrawal phenomena, and 4) opiate-induced tolerance and hyperalgesia develop differently based on gender and/or ethnicity.
The study is the first quantitative and prospective examination of tolerance and hyperalgesia in pain patients and may have important implications for the rational use of opioids in the treatment of chronic pain.
Sheila E. Cohen
Professor (Clinical) of Anesthesia, Emerita
Current Research and Scholarly Interests Our obstetric anesthesia group is interested in a variety of topics including the efficacy and mechanism of action of spinal and epidural opioids for production of analgesia during labor, and the functionality of epidural analgesia for labor pain relief.
Robert Cowan, MD, FAAN
Clinical Professor, Neurology & Neurological Sciences
Current Research and Scholarly Interests Current interest focus on patient education technology and patient/physician communication with a particular emphasis on tools which increase encounter efficiency and improve outcomes. Basic research focuses on mechanisms of action in Chronic Daily Headache, with a particular emphasis on New Daily Persistent Headache. Techniques include fMRI, biomarker investigation and evoked potentials. Clinical research includes clinical trials of novel treatments for episodic and chronic headache forms.