School of Medicine
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Amato J. Giaccia
Jack, Lulu and Sam Willson Professor, Professor of Radiation Oncology, and by courtesy, of Obstetrics and Gynecology and of Surgery
Current Research and Scholarly Interests During the last five years, we have identified several small molecules that kill VHL deficient renal cancer cells through a synthetic lethal screening approach. Another major interest of my laboratory is in identifying hypoxia-induced genes involved in invasion and metastases. We are also investigating how hypoxia regulates gene expression epigenetically.