School of Medicine
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Professor of Biochemistry and of Microbiology and Immunology
Current Research and Scholarly Interests We study the interactions between infectious bacteria and the human host cell actin cytoskeleton. Listeria monocytogenes and Shigella flexneri are unrelated food-borne bacterial pathogens that share a common mechanism of invasion and actin-dependent intercellular spread in epithelial cells. Our studies fall into three broad areas: the biochemical basis of actin-based motility by these bacteria, the biophysical mechanism of force generation, and the evolutionary origin of pathogenesis.
Lucy Becker Professor in Medicine and of Microbiology and Immunology
Current Research and Scholarly Interests Genetic and cellular basis of pathogenicity of Helicobacter pylori. Molecular epidemiology, hospital epidemiology, quality improvement in healthcare associated infections.