School of Medicine
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Associate Professor of Genetics and, by courtesy, of Statistics
Current Research and Scholarly Interests Develop statistical and computational methods for population genomics analyses; modeling human evolutionary history; genetic association studies in admixed populations.
Jean Y. Tang MD PhD
Associate Professor of Dermatology at the Stanford University Medical Center
Current Research and Scholarly Interests My research focuses on 2 main areas:
1. Skin cancer:
- New therapeutics to treat and prevent non-melanoma skin cancer, especially by targeting the Hedgehog signaling pathway for BCC tumors
- Genomic analysis of drug-resistant cancers
- Identifying risk factors for skin cancer in the Women's Health Initiative
2. Epidermolysis Bullosa: gene therapy and protein therapy to replace defective/absent Collagen 7 in children and adults with Recessive Dystrophic EB
Melinda L. Telli, M.D.
Assistant Professor of Medicine (Oncology) at the Stanford University Medical Center
Current Research and Scholarly Interests My research focuses on breast cancer treatment and survivorship. My primary research interest is the development of novel strategies for the treatment of early stage triple-negative and BRCA1/2 mutation-associated breast cancer. Other areas of interest include prevention of cardiac damage associated with breast cancer treatment and cardiotoxicity of anti-cancer agents.
Associate Professor of Obstetrics and Gynecology (Oncology)
Current Research and Scholarly Interests Gynecologic Malignancies
Biologic Response Modifiers
New Drug Development
Antigenic specificities of human antibodies encoded by the VH4-34 gene
Mary Frances Nunez Teruel
Assistant Professor of Chemical and Systems Biology
Current Research and Scholarly Interests The Teruel Lab uses a combination of engineering and biological approaches including high-throughput screening of RNAi and DNA construct libraries, targeted mass spectrometry, live-cell fluorescence microscopy, and bioinformatics to investigate the systems biology of cell differentiation and cell signaling with particular focus on uncovering the molecular mechanisms underlying insulin resistance, diabetes, and obesity.
Postdoctoral Research fellow, Stanford Cancer Center
Current Research and Scholarly Interests Whilst cancer is first a disease of unregulated cell proliferation, a small proportion of cells within a tumour are paradoxically in a relative state of quiescence. These chemotherapy-resistant cells are the likely culprits responsible for relapse but the signalling events that control this state are unknown. By studying purified populations of cancer stem cells derived from patients with acute myeloid leukemia my work is focused on defining novel targets for future therapy.
Sara L. (Sally) Tobin
Sr Research Scholar, Pediatrics - Center for Biomedical Ethics
Current Research and Scholarly Interests Tobin is a Senior Research Scholar at the Stanford Center for Biomedical Ethics. She obtained her Ph.D. in Developmental Biology from the University of Washington and did postdoctoral research in Genetics at the University of California, Berkeley and in Biochemistry at the University of California, San Francisco. She became a faculty member at the University of Oklahoma College of Medicine in 1983 and moved to Stanford University in 1996. Her research contributions have been published in prestigious journals such as Cell, Nature, Genes & Development, Neuron, and Journal of Cell Biology.
With her collaborator, graphic designer Ann Boughton, Tobin has completed the production of three educational multimedia CD-ROM discs about the genetic revolution in medical care sparked by the rapid advances in our knowledge about the human genome. An on-line version derived and updated from these CDs is pending release through Twisted Ladder Media, and is entitled: "The New Genetics: Medicine and the Human Genome. Molecular Concepts, Applications, and Ramifications." In addition, Tobin and Boughton have collaborated on educational websites on inherited risk of breast cancer and on hereditary colorectal cancer with the Stanford Cancer Genetics Clinic.
Tobin's current major research interests include an educational project funded by the National Science Foundation to create and evaluate innovative modules for undergraduates entitled, "The New Genetics: Electronic Tools for Educational Innovation." The modules are presented in on-line form as an electronic course and are accompanied by workbook exercises and problem sets. The content includes principles of genetics, molecular genetic technologies, applications in medicine, environmental biology, agriculture, and society, as well as implications. In addition, she is collaborating on two projects that are exploring the ramifications of using genetic information about addiction risk in the judicial system.
Tobin is a member of the Benchside Consultation Team for the Center for the Integration of Research on Genetics and Ethics, and she evaluates clinical protocols for ethical issues for the Clinical Translational Research Program.
Clare J. Twist
Associate Professor of Pediatrics (Hematology/Oncology) at the Lucile Salter Packard Children's Hospital
Current Research and Scholarly Interests My primary research interest is in the study and treatment of neuroblastoma. My clinical interests also include Wilms tumor, hepatoblastoma, post-transplant lymphoproliferative disorders, phase I therapies for hematologic malignancies, as well as palliative and end of life care.