School of Medicine
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Roham Zamanian, MD, FCCP
Associate Professor of Medicine (Pulmonary and Critical Care Medicine) at the Stanford University Medical Center
Current Research and Scholarly Interests 1. Development and evaluation of prognostic and diagnostic integral biomarkers in PAH.
2. Prevalence and Treatment of Insulin Resistance in PAH.
3. Role of inflammation and proteomic signature in PAH
4. Development of novel therapeutics (bench to bedside) including FK506 & Elastase Inhibition in PAH.
5. Assessment of Vasoreactivity (gain and loss) in pulmonary arterial hypertension
6. Assessment of microvascular function in PAH.
Marta Gaia Zanchi
Bio I am the creator and Lead Director of the Byers Center for Biodesign's course and project immersion program "Biodesign for Mobile Health" (BMH) examining the emerging mobile health industry (2012-present). This diverse, interactive, interdisciplinary, team and project-oriented course has been named by Stanford's Bioengineering "one of the flagship courses of our Department" and has trained nearly 200 students in a process of health technology innovation grounded on the understanding of contemporary Mobile Health needs.
Currently Faculty member (Lecturer) at Stanford University in the School of Medicine, I am working with the Byers Center for Biodesign community under the direct supervision of Paul Yock, MD, Director of the Center and Founding Co-Chair of Stanford's Department of Bioengineering.
In addition to my role as Faculty member and course Lead Director, I am a member of the Biodesign Leadership Group and a mentor to both Biodesign Fellows and students from the School of Medicine, all major Engineering schools and the Graduate School of Business. Together with a mHealth Advisory Group of thought leaders at Stanford, I help inform Stanford School of Medicine's thinking and strategy around Mobile Health to accelerate projects and foster quality research.
Biodesign for Mobile Health (on Canvas): canvas.stanford.edu/courses/44010
Byers Center for Biodesign: biodesign.stanford.edu/bdn/index.jsp
At Stanford, I also have the pleasure to advise on the board of SHIFT, a student initiative aiming to promote and cultivate health innovation on campus by creating a forum for developers, entrepreneurs, and pre-health students to collaborate. A motivated leadership team envisions the group as a platform that connects and empowers students with resources and opportunities to innovate in healthcare. SHIFT fulfills its mission through open roundtable discussions, the TreeHacks Health hackathon and a fellowship program that pairs students as health++ fellows with early-stage companies or faculty-sponsored projects.
Follow this link to learn more:
SHIFT Health + Tech @Stanford: shift.stanford.edu
When I am not at Stanford, you'll find me consulting, advising or otherwise engaging with and learning from the startup community of Silicon Valley. I am the Managing Director of Medinnovo LLC, advisory board (AB) member of many exciting privately-held companies, and founders' board of advisors (FBA) member at StartX MED, a startup accelerator.
And, more links:
My LinkedIN Profile: linkedin.com/in/mgzanchi
Medinnovo LLC: medinnovo.com
StartX Accelerator: startx.com
Marta Gaia Zanchi
c/o Stanford Biodesign
318 Campus Drive, Room E100
Stanford, CA 93405-5428
"Tell me and I forget, teach me and I may remember, involve me and I learn."
— Benjamin Franklin
Marguerite Blake Wilbur Professor in Natural Science and Professor, by courtesy, of Physics
Current Research and Scholarly Interests My research group is exploring a variety of topics that range from the basic understanding of chemical reaction dynamics to the nature of the chemical contents of single cells.
Under thermal conditions nature seems to hide the details of how elementary reactions occur through a series of averages over reagent velocity, internal energy, impact parameter, and orientation. To discover the effects of these variables on reactivity, it is necessary to carry out studies of chemical reactions far from equilibrium in which the states of the reactants are more sharply restricted and can be varied in a controlled manner. My research group is attempting to meet this tough experimental challenge through a number of laser techniques that prepare reactants in specific quantum states and probe the quantum state distributions of the resulting products. It is our belief that such state-to-state information gives the deepest insight into the forces that operate in the breaking of old bonds and the making of new ones.
Space does not permit a full description of these projects, and I earnestly invite correspondence. The following examples are representative:
The simplest of all neutral bimolecular reactions is the exchange reaction H H2 -> H2 H. We are studying this system and various isotopic cousins using a tunable UV laser pulse to photodissociate HBr (DBr) and hence create fast H (D) atoms of known translational energy in the presence of H2 and/or D2 and using a laser multiphoton ionization time-of-flight mass spectrometer to detect the nascent molecular products in a quantum-state-specific manner by means of an imaging technique. It is expected that these product state distributions will provide a key test of the adequacy of various advanced theoretical schemes for modeling this reaction.
Analytical efforts involve the use of capillary zone electrophoresis, two-step laser desorption laser multiphoton ionization mass spectrometry, cavity ring-down spectroscopy, and Hadamard transform time-of-flight mass spectrometry. We believe these methods can revolutionize trace analysis, particularly of biomolecules in cells.