School of Medicine
Showing 221-230 of 236 Results
Joseph C. Wu
Simon H. Stertzer, MD, Professor and Professor of Radiology
Current Research and Scholarly Interests Drug discovery, drug screening, and disease modeling using biobank of cardiac iPSC lines.
Joy Wu, MD, PhD
Assistant Professor of Medicine (Endocrinology)
Current Research and Scholarly Interests My laboratory focuses on the pathways that regulate the differentiation of mesenchymal stem cells into the osteoblast and adipocyte lineages. We are also studying the role of osteoblasts in the hematopoietic stem cell niche and B lymphocyte development in the bone marrow microenvironment.
Sean M. Wu, MD, PhD, FACC
Associate Professor of Medicine (Cardiovascular Medicine) and, by courtesy, of Pediatrics
Current Research and Scholarly Interests My lab seeks to identify mechanisms regulating cardiac lineage commitment during embryonic development and the biology of cardiac progenitor cells in development and disease. We believe that by understanding the transcriptional and epigenetic basis of cardiomyocyte growth and differentiation, we can identify the most effective ways to repair diseased adult hearts. We employ mouse and human embryonic and induced pluripotent stem cells as well as rodents as our in vivo models for investigation.
Postdoctoral Research fellow, Psychiatry
Bio Wei Wu received the PhD degree in Biomedical Engineering from Tsinghua University, China, in 2012. From 2008 to 2010, he was a visiting student at the Neuroscience Statistics Laboratory, MIT, directed by Dr. Emery Brown. He is an associate editor of Neurocomputing and a member of IEEE Biomedical Signal Processing Technical Committee.
Postdoctoral Research fellow, Neurosurgery
Bio I am interested in the neural circuits for motor control and how it is affected under the progression of Parkinson’s disease (PD). Currently I focus on dissecting the role of the striatal spiny projection neurons on integrating information from other brain areas, which are highly altered in PD. By incorporating various tools and state-of-the-art approaches, such as two-photon imaging/uncaging, patch-clamp electrophysiology, optogenetic manipulation of neural circuit and computational simulation, I aim to provide a comprehensive view, in the neuronal circuitry level, of how motor control is achieved and what goes wrong during the pathophysiological changes in PD, so that potential new therapeutic targets will be discovered to help PD patients.
My past training has quipped me with various research skills including:
1.Brain slice electrophysiology for studying ion channel physiology and synaptic transmission.
2.Two-photon calcium imaging for monitor subcellular neuronal activity in brain slices and in vivo.
3.Optics and microscopy development.
4.Computer programming for image processing, data analysis, and instrumental control.
5.Optogenetic techniques for controlling targeted neuronal circuits with transgenic mice and AAV viral injection.
6.Immunohistochemistry and biochemical essays.
These skills enable me not only to design and perform bench works independently but also capable to have a working model and a big picture in mind. I have a solid background in biology and neurophysiology, and my broad research skills further facilitate collaboration with experts from multidisciplinary. In summary, I have demonstrated a record for successfully completing research projects, and my strong motivation and substantial research skills have prepared me well to achieve my goal.
Postdoctoral Research fellow, Pathology
Current Research and Scholarly Interests study human neurodegeneration diseases via drosophila models