Bio

Professional Education


  • Bachelor of Engineering, Vrije Universiteit Brussel (2003)
  • Master of Science in Engr, Vrije Universiteit Brussel (2006)
  • Master of Science, Vrije Universiteit Brussel (2006)
  • Doctor of Philosophy, Vrije Universiteit Brussel (2010)

Stanford Advisors


Publications

All Publications


  • How Does the Xenopus laevis Embryonic Cell Cycle Avoid Spatial Chaos? CELL REPORTS Gelens, L., Huang, K. C., Ferrell, J. E. 2015; 12 (5): 892-900

    Abstract

    Theoretical studies have shown that a deterministic biochemical oscillator can become chaotic when operating over a sufficiently large volume and have suggested that the Xenopus laevis cell cycle oscillator operates close to such a chaotic regime. To experimentally test this hypothesis, we decreased the speed of the post-fertilization calcium wave, which had been predicted to generate chaos. However, cell divisions were found to develop normally, and eggs developed into normal tadpoles. Motivated by these experiments, we carried out modeling studies to understand the prerequisites for the predicted spatial chaos. We showed that this type of spatial chaos requires oscillatory reaction dynamics with short pulse duration and postulated that the mitotic exit in Xenopus laevis is likely slow enough to avoid chaos. In systems with shorter pulses, chaos may be an important hazard, as in cardiac arrhythmias, or a useful feature, as in the pigmentation of certain mollusk shells.

    View details for DOI 10.1016/j.celrep.2015.06.070

    View details for Web of Science ID 000358999800016

    View details for PubMedID 26212326

  • Effects of inhomogeneities and drift on the dynamics of temporal solitons in fiber cavities and microresonators OPTICS EXPRESS Parra-Rivas, P., Gomila, D., Matias, M. A., Colet, P., Gelens, L. 2014; 22 (25): 30943-30954
  • Spatial trigger waves: positive feedback gets you a long way MOLECULAR BIOLOGY OF THE CELL Gelens, L., Anderson, G. A., Ferrell, J. E. 2014; 25 (22): 3486-3493
  • Third-order chromatic dispersion stabilizes Kerr frequency combs OPTICS LETTERS Parra-Rivas, P., Gomila, D., Leo, F., Coen, S., Gelens, L. 2014; 39 (10): 2971-2974

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